Cori Gorman, PhD, MBA
With twenty-five years experience in the
biotechnology industry, Dr. Gorman has worked in all aspects
of the biotechnology industry, including raising capital,
strategic planning and developing infrastructure. She has
helped early stage biotechnology companies raise over $ 80
million (federal funds and VCs) and has closed over 25
partnerships in a corporate development capacity. She has
used this experience to chair a number of sessions on
business models and financing for early stage companies at
BIO and Bio-Europe conferences. She has been a guest
lecturer on the business of biotechnology at Yale and at
Haas Business School, UC Berkeley. Under her vision, DNA
Bridges Inc. has expanded its reach beyond the US into
Europe and Australia.
Her experience in the biotechnology
industry includes a ten-year period at Genentech where she
helped to develop of a number of marketed products including
Kogenate, Activase, Herceptin, Xolair, and Raptiva. Based on
her work at Genentech, Cori is also recognized as a pioneer
in the development of monoclonal antibody therapeutics and
has co-authored 6 INDs. Upon leaving her position at
Genentech, Cori co-founded two biotech start-ups, one of
which, Valentis, went public.
Dr. Gorman has an outstanding record of
achievement in basic research and drug development. Dr. Cori
Gorman is an inventor on nine issued patents in the fields
of gene expression and delivery and gene therapy and is
recognized as one of the most highly cited people in her
field in the last two decades. Dr. Gorman developed the CAT
assay, which was the industry standard for more than fifteen
years. Her scientific work has received over 10,000
Cori has received several fellowships from
such organizations as the American Cancer Society, the
National Cancer Institute, the European Molecular Biology
Organization and NATO.
complexes for gene targeting
Method for preparing
soluble analogues of integrins
complexes for gene targeting
Soluble analogues of
Host cells and method of
producing soluble analogues of integrins
system for producing recombinant protein
and Bullock C. (2000) Site-specific integration techniques
for achieving sustained gene expression. Current Opinion in
Biotechnology in press.
Bullock C. and
Gorman, CM. (2000) CAT as a reporter. Methods in
Enzymoogy, in press
M, Gilkey,L, Watral, V, Fox, B, Bullock, C, Fradkin, L,
Liggitt, D, Roche, L, Bussey, LB and Gorman, CM
(1999) Transient transgenesis using lipid-DNA delivery. DNA
& Cell Biology DNA Cell Biology. 18:533-547.
(1998) Aerosol delivery of lipid:DNA complexes to lung
of Rhesus monkey. Pharm. Res . 15:671-679.
Aikawa, M., Fox, B., Fox, E., Lapuz, C., Michaud, B.,
Nguyen, H., Roche, E., Sawa, T and Weiner-Kronish, JP (1997)
Efficient in vivo delivery of DNA to pulmonary cells using
the novel lipid EDMPC. Gene Therapy 4:983- 992.
Richard J, Arboleda Jane, Reese David M Wongvipat Nancy,
Pegram Mark D Ramos Lillian, Gorman, CM, Parker
Malcolm G, Sliwkowski Mark X, Slamon Dennis J. (1995) HER-2
tyrosine kinase pathway targets estrogen receptor and
promotes hormone-independent growth in human breast cancer
cells. Oncogene 10:2435-2446.
Shields R, O'Connell L, Lahr S, Porter J, Gorman CM,
Jardieu P. (1994) The binding site on human immunoglobulin E
for its high affinity receptor. J Biol Chem 269:26368-26373.
J, Goodman Laurie J, Gorman, CM, Wells James A.
(1994) A Survey of furin substrate specifically using
substrate phage display. Protein structure Functions.
Protein Science 3:1197-1205.
J, Gorman, CM. (1994) Autoproteolytic activation of
the mouse prohormone convertase MPC1. BBRC 201:795-804.
Sliwkowski M, Gorman, CM. (1994) Constitutive
secretion of active insulin by epithelial cells. JBC
Presta L G,
Lahr S J, Shields R L, Porter J P, Gorman, CM, Fendly
B M, Jardieu P M. (1993) Humanization of an antibody
directed against IgE. Journal of Immunology
Gillece-Castro B, Gorman, CM (1992) Prohormone
Convertase-1 will process pro-relaxin, a member of the
insulin family of hormones. Mol. Endo. 6:1441-1450.
Schmelzer C H,
Burton L E, Chan W-P, Martin E, Gorman, CM,
Canova-Davis E, Ling V T, Sliwkowski M B, McCray G, Briggs J
A, Nguyen T H, Polastri G. (1992) Biochemical
characterization of recombinant human nerve growth factor.
J. of Neurochem. 59:1675-1683.
Presta L, Gorman, CM, Ridgway J, Henner D,
Wong W, Rowland A, Kotts C, Carver M, Sheppard M. (1992)
Humanization of an anti-p 185 Her2 antibody for human cancer
therapy. Proc. Natl. Acad. Sci. 89:4285-4289.
Caras I, Fisher K, Gorman, CM. (1991) Lipid
association, but not the transmembrane domain, is required
for tissue factor activity. J. Biol. Chem. 226:21911-21916.
Choi T, Huang
M, Gorman, CM, Jaenisch R. (1991) A generic intron
increases gene expression in transgenic mice. Mol. and Cell.
(1990) Mammalian cell expression. Current Opinion in
Fendly B M, Fisher K, Lawn R, Marks B J, McCray G, Tate K,
Vehar G, Gorman, CM. (1990) Mammalian cell transient
expression of tissue factor for the production of antigen.
Protein engineering 3 (6):547-553.
Gorman, CM. (1990) The simian virus 40 small t intron,
present in many common expression vectors, leads to aberrant
splicing. Molecular Cell Biology 10(4):1805-1810.
CM, Gies D, McCray G. (1990) Transient production of
proteins using adenovirus transformed cell line. DNA protein
engineering techniques 2 (1):3-10.
Gorman, CM. (1990) Intervening sequence increases
efficiency of RNA 3' processing and accumulation of
cytoplasmic RNA. Nucleic Acids Reg. 18(4):937-47.
** Pritchett D
B, Sontheimer H, Gorman, CM, Kettenmann H, Seeburg P,
Schofield P. (1988) Ligand-gating and allosteric
potentiation of human GABA receptor subunits in a transient
mammalian cell expression system. Science 242:1306-1308.
Eaton D L,
Wood W, Eaton D, Hass P, Hollingshead P, Wion K, Mather J,
Lawn R, Vehar G, Gorman, CM. (1986) Construction and
characterization of an active Factor VIII variant lacking
the central one-third of the Molecule. Biochemistry
CM, Rigby P W J, Lane D P. (1985) Negative regulation of
viral enhancers in undifferentiated embryonic stem cells.
CM. (1985) High efficiency gene transfer. DNA Cloning a
Practical Approach. ed. Glover D M, IRL Press.
Lane D P, Rigby PW J. (1984) High efficiency gene transfer
into mammalian cells. Phil. Trans. R. Soc. Lond.
CM, Howard B, Reeves R. (1983) Expression of recombinant
plasmids in mammalian cells is enhanced by sodium butyrate.
Nucleic Acids Res. 11:7631.
CM, Padmanabhan R, Howard B. (1983) High efficiency
DNA-mediated transformation of primate cells. Science
CM, Merlino G, Willingham M, Pastan I, Howard B. (1982)
The Rous sarcoma virus LTR is a strong promoter in a variety
of cell types when introduced by DNA mediated transfection.
Proc. Natl. Acad. Sci. USA 79:6777-6781
Khoury G, Gorman, CM, Howard B, Gruss P. (1982) Host
specific activation of transcription by tandem repeats from
SV40 and Maloney sarcoma virus. Proc. Natl. Acad. Sci. USA
CM, Moffat L, Howard B. (1982) Recombinant genomes that
express chloramphenicol acetyltransferase in mammalian
cells. Mol. Cell. Biol. 2:1044-1051.
Scientific work cited over 13,000 times,
including nine classic citations
Recipient of American Cancer Society Fellowship
Recipient of NATO Fellowship
Recipient of European Molecular Biology Organization (EMBO)
Outstanding Teaching Assistant Washington State University
Graduated Sigma Cum Laude University of Texas El Paso
One of the Top Ten Graduates University of Texas El Paso
"Cori Gorman has an
extraordinarily high level of expertise, which
was one of the critical factors in choosing her
for this. When things come up again, she is the
person I will go to."
- Senior scientist at a biotechnology company.